Homemade Mississippi Comeback Sauce Recipe

Meet your new favorite dipping sauce—this Homemade Mississippi Comeback Sauce is creamy, tangy, and totally addictive! Once you try it, you’ll be coming back for more every time.

Classic Mississippi Comeback Sauce is a Southern staple known for its bold, zesty flavor and creamy texture. Made with a blend of mayonnaise, ketchup, hot sauce, and spices, it’s the ultimate all-purpose condiment—perfect for dipping fries, slathering on burgers, drizzling over salads, or pairing with fried seafood. True to its name, once you try it, you’ll keep coming back for more!

Today, I served it with a batch of Air Fryer Fried Shrimp, and you can also serve it with a homemade set of Air Fryer Onion Rings or even a collection of Air Fryer Chicken Wings.

Why You Will Love This Recipe!

• Ridiculously Easy to Make – Just mix a handful of pantry staples—no cooking required!
• Packed with Bold Flavor – Creamy, tangy, a little spicy, and totally crave-worthy.
• Versatile – Use it as a dip, spread, salad dressing, or drizzle—it works with everything.
• Customizable Heat – Make it mild or kick it up a notch with extra hot sauce or cayenne.
• Better Than Store-Bought – Fresher, tastier, and you know exactly what’s in it!

Ingredients Needed

• Mayonnaise – Creamy base that gives the sauce its richness

• Chili Sauce – Adds tangy sweetness with a subtle kick
• Ketchup – Brings familiar tomato flavor and extra smoothness
• Worcestershire Sauce – Deep, savory umami that boosts overall flavor
• Lemon Juice – Brightens the sauce with a citrusy zing
• Paprika – Adds mild spice and a smoky undertone
• Garlic (minced) – Fresh, sharp bite for bold, aromatic depth
• Yellow Onion (minced) – Sweet, subtle crunch with savory flavor
• Hot Sauce – Optional heat to match your spice preference

How to Make Comeback Sauce from Scratch

Mix the Base – In a bowl, combine mayonnaise, chili sauce, and ketchup. Stir until smooth and creamy.

Add the Flavor Boosters – Stir in Worcestershire sauce, lemon juice, paprika, minced garlic, and minced onion. Mix well to blend all the flavors.

Adjust the Heat – Add hot sauce to taste, depending on how spicy you like it.

Chill for Best Flavor – Cover and refrigerate the sauce for at least 30 minutes to let the flavors meld. It gets even better after a few hours!

Serve & Enjoy – Use as a dip, spread, or dressing for everything from fries and burgers to seafood and salads.

Dukes Mississippi Comeback Sauce Recipe Tips

• Use Duke’s Mayo for Authentic Flavor – Its tangy, rich taste gives the sauce its signature Southern flair.
• Let It Chill – For the best flavor, refrigerate the sauce for at least 30 minutes before serving to let the ingredients meld together.
• Adjust the Heat – Add hot sauce gradually and taste as you go to customize the spice level.
• Finely Mince Onion and Garlic – A fine texture ensures the sauce stays smooth and spreadable.
• Make It Ahead – This sauce tastes even better the next day and lasts up to a week in the fridge.
• Stir Before Serving – Ingredients may separate slightly in the fridge—just give it a quick stir before using.
• Try Variations – Add a pinch of cayenne, smoked paprika, or a dash of pickle juice for your own twist.

Storing

Store Homemade Mississippi Comeback Sauce in an airtight container or jar in the refrigerator for up to one week. Be sure to give it a good stir before each use, as the ingredients may naturally separate over time.

What To Serve With Homemade Mississippi Comeback Sauce Recipe

Homemade Mississippi Comeback Sauce is incredibly versatile and pairs well with a variety of dishes. It’s perfect for dipping crispy fries, onion rings, or sweet potato fries.

You can also drizzle it over grilled or fried seafood like shrimp and catfish, or use it as a topping for burgers, sandwiches, and wraps. For a refreshing twist, try it as a salad dressing or serve it with fresh veggies like carrots, celery, or cucumber for a crunchy snack. The creamy, tangy, and spicy flavors elevate almost any dish, making it a must-have in your kitchen!

Homemade Mississippi Comeback Sauce Recipe Faqs

Can I adjust the spice level of the sauce? Yes, you can easily control the spice by adding more or less hot sauce to taste. For a milder version, use just a small amount or skip it altogether.

How long does Homemade Mississippi Comeback Sauce last? Stored in an airtight container in the fridge, the sauce will stay fresh for up to a week. Make sure to stir it before using, as it may separate slightly over time.

Can I make the sauce ahead of time? Absolutely! In fact, the flavor improves as it sits, so making it ahead of time is a great idea. Let it chill in the fridge for at least 30 minutes before serving.

What if I don’t have chili sauce? If you don’t have chili sauce, you can substitute with ketchup and a little bit of hot sauce or even a dash of chili powder for that tangy kick.

What can I serve Mississippi Comeback Sauce with? This sauce is incredibly versatile! It’s great as a dip for fries, onion rings, or fried seafood, and it also works as a topping for burgers, sandwiches, or even as a salad dressing.

Can I make it creamy without mayonnaise? You can use Greek yogurt or sour cream as a substitute for mayo, though the flavor may be slightly different. You may need to adjust the other seasonings to balance the taste.

Can I use this sauce for meal prep? Yes, it’s perfect for meal prep! The sauce keeps well in the fridge, and you can use it throughout the week for various meals and snacks.

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• Air Fryer KFC Fried Chicken
• KFC Copycat Potato Wedges (Air Fryer)
• KFC Honey BBQ Wings
• Air Fryer Copycat KFC Popcorn Chicken
• Air Fryer Copycat KFC Spicy Chicken Sandwich
• Air Fryer Copycat KFC Biscuits
• KFC Original Recipe Chicken (Copycat)
• Copycat KFC Honey Mustard Sauce
• Air Fryer Mashed Potatoes

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