Rich, hearty and super cheesy, this Air Fryer Guinness Cheddar Meatloaf is a guaranteed crowd-pleaser! With a deep, malty flavor of Guinness and loaded with sharp cheddar cheese, this meatloaf takes comfort food to the next level!

Air Fryer Guinness Cheddar Meatloaf with melted cheese and Guinness-infused flavor.
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And if all those flavors aren’t already amazing, it’s also topped with a tangy glaze that perfectly balances the robust flavors. It’s official, this is the ultimate recipe for meatloaf lovers! 

Whether you’re planning a cozy dinner at home or need an easy meal prep option, this meatloaf is both versatile and packed with flavor. Works really well served with creamy mashed potatoes or roasted veggies.

Craving more delicious meatloaf recipes? Check out my Air Fryer Meatloaf with Bourbon Glaze, Air Fryer Turkey Meatloaf, Golden Corral Meatloaf Recipe or this delicious Air Fryer Chicken Meatloaf. 

Air Fryer Guinness Cheddar Meatloaf with rich beer flavor and melted cheddar cheese.

Why You’ll Love This Recipe!

  • Quick and Easy: This Air Fryer Guinness Cheddar Meatloaf is not only delicious, but it only takes a few minutes to prepare. It also cooks so much faster in the air fryer! 
  • Delicious Flavors: Guinness beer and cheddar cheese go really well together, making this meatloaf really special and delicious. 
  • Perfect Texture: The air fryer ensures the meatloaf is juicy on the inside and slightly crispy on the outside, with a perfectly caramelized top! 
  • Customizable: You can easily adapt the ingredients and seasonings to suit your taste and preferences.

Ingredients You’ll Need

Ingredients needed for Air Fryer Guinness Cheddar Meatloaf on kitchen table.
  • Ground meat – I recommend ground beef for the best balance of flavor and texture. You can also choose pork and beef mix for extra fattiness and flavor. 
  • Breadcrumbs – Helps bind the meatloaf while keeping it moist. You can use plain or seasoned breadcrumbs.
  • Cheddar cheese – Any kind of shredded cheese works, so use your favorite. I like to use mature cheddar for extra flavor. 
  • Guinness beer – The star of this recipe that adds a subtle depth and richness. 
  • Onion – Finely chopped and sautéed. I recommend using regular cooking onions, but you can also use red onions for a sweeter flavor. 
  • Worcestershire sauce and Dijon mustard – Bring bold, savory notes to the mix.
  • Seasonings – Garlic powder, onion powder, salt, and pepper for a well-rounded flavor. Feel free to add any other seasonings you like.

How to Make Air Fryer Guinness Cheddar Meatloaf

Cooking finely chopped onion in oil, adding Guinness beer to simmer and reduce.

Step One: In a skillet, cook the finely chopped onion in a bit of oil until translucent. Add the Guinness beer and simmer until reduced, intensifying its flavor.

Combining meatloaf ingredients in a bowl, mixing until just combined to keep it tender.

Step Two: In a large bowl, combine all the meatloaf ingredients. Mix until just combined and don’t overmix to keep the meatloaf tender.

Forming meatloaf into a loaf shape, cooking at 375°F, and adding topping midway through.

Step Three: Form the mixture into a loaf shape that fits your air fryer basket. Cook at 375°F (190°C) for 20 minutes. While the meatloaf cooks, mix the ketchup, Dijon mustard, and honey. After 20 minutes, spread the topping evenly over the meatloaf and continue cooking for another 15–20 minutes, or until the internal temperature reaches 160°F (70°C).

Step Four: Let the meatloaf rest for 5–10 minutes before slicing. Pair it with mashed potatoes, roasted veggies, or a crisp salad.

Air Fryer Guinness Cheddar Meatloaf with melted cheddar cheese and rich Guinness flavor.

Flavor Variations

  • Bacon-Wrapped: Wrap the meatloaf in strips of bacon before air frying for a smoky twist.
  • Spicy Kick: Add a diced jalapeño or a pinch of cayenne pepper to the mix for a bit of heat.
  • Herb-Infused: Mix in fresh herbs like thyme or parsley for a fresher, aromatic flavor.
  • Cheese Swap: Use smoked gouda or pepper jack instead of cheddar for a new flavor profile.

Tips & Tricks

  • Don’t overmix: Overmixing can make the meatloaf dense. Combine the ingredients until just mixed.
  • Check for doneness: Use a meat thermometer to ensure the internal temperature reaches 160°F (70°C) for perfectly cooked meatloaf.
  • Easy cleanup: Line your air fryer basket with parchment or foil to prevent sticking and make cleanup faster.
  • Let it rest: Resting the meatloaf helps the juices redistribute, making each slice more tender.
Air Fryer Guinness Cheddar Meatloaf with gooey cheddar and rich Guinness beer flavor.

Frequently Asked Questions

What’s the best way to store leftovers? Store leftover meatloaf in an airtight container in the refrigerator for up to 3 days. Reheat slices in the air fryer at 350°F for 5–7 minutes.

Can I freeze this meatloaf? Absolutely! Wrap the cooked and cooled meatloaf tightly in foil or plastic wrap, then place it in a freezer-safe bag. Freeze for up to 3 months. Defrost in the fridge overnight before reheating.

What sides go best with this meatloaf? Mashed potatoes, steamed green beans, or a crisp garden salad are perfect pairings for this hearty dish.

Air Fryer Guinness Cheddar Meatloaf with melted cheddar and a Guinness-infused flavor.

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Air Fryer Guinness Cheddar Meatloaf with melted cheese and Guinness-infused flavor.

Air Fryer Guinness Cheddar Meatloaf

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Prep Time: 10 minutes
Cook Time: 30 minutes
Total Time: 40 minutes
Servings: 8 Servings

Description

Make a flavorful Air Fryer Guinness Cheddar Meatloaf in no time! This juicy meatloaf is infused with the rich taste of Guinness beer and cheddar cheese, cooked perfectly in your air fryer.

Ingredients 

  • 1 pound ground beef, or a mix of beef and pork
  • 1/2 cup breadcrumbs, plain or seasoned
  • 1/4 cup milk
  • 1 large egg, lightly beaten
  • 1/2 cup shredded cheddar cheese
  • 1/4 cup Guinness beer
  • 1 tablespoon Worcestershire sauce
  • 1 tablespoon Dijon mustard
  • 1 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • 1/2 teaspoon black pepper
  • 1/2 teaspoon salt

Topping Ingredients:

  • 2 tablespoons ketchup
  • 1 tablespoon Dijon mustard
  • 1 tablespoon honey

Instructions

  • In a skillet, heat a bit of oil and cook the finely chopped onion until translucent. Add the Guinness beer and simmer until it reduces, deepening the flavor.
  • In a large bowl, combine all the meatloaf ingredients and mix until just combined—avoid overmixing to keep the meatloaf tender. Shape the mixture into a loaf that fits your air fryer basket and cook at 375°F (190°C) for 20 minutes.
  • While the meatloaf is cooking, prepare the topping by mixing ketchup, Dijon mustard, and honey. After 20 minutes, spread the topping evenly over the meatloaf and cook for an additional 15–20 minutes, or until the internal temperature reaches 160°F (70°C).
  • Allow the meatloaf to rest for 5–10 minutes before slicing. Serve with mashed potatoes, roasted veggies, or a crisp salad for a complete meal.

Equipment

  • Cooking Spray
  • Parchment Paper, optional

Nutrition

Serving: 1ServingCalories: 167kcalCarbohydrates: 10gProtein: 16gFat: 7gSaturated Fat: 3gPolyunsaturated Fat: 1gMonounsaturated Fat: 2gTrans Fat: 0.2gCholesterol: 66mgSodium: 393mgPotassium: 277mgFiber: 1gSugar: 4gVitamin A: 141IUVitamin C: 0.5mgCalcium: 87mgIron: 2mg

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