Start by cleaning your mushrooms: With a wet paper towel, wipe down your mushrooms.
Then, mix the panko (or breadcrumbs), Parmesan Cheese, garlic powder, onion powder, salt, and black pepper in a small bowl.
In another bowl, add your eggs, and whisk with a fork. Add the flour to the third bowl.
Then dip your cleaned mushrooms into the flour mixture, then the egg mixture, and finally the bread crumb mixture. Make sure to let the excess egg drip off before adding it to the bread crumb mixture. I double-dipped my mushrooms back into the egg and then the bread crumbs to make sure they were fully coated.
As you coat them place them on a greased air fryer basket or tray.
Spray the mushrooms with cooking spray.
Set the tray into the air fryer, and set the temperature to 375 degrees F, air fryer setting, for 10 to 12 minutes.
Flip the mushrooms, and spray again about halfway through the cooking process.
Plate, serve, and enjoy!