In a large bowl, mix the shredded chicken, cheese, salsa, garlic powder, onion powder, cumin, chili powder, salt, and black pepper until well combined.
Lay out the tortillas and spoon the chicken mixture evenly down the center of each one.
Fold in the sides, then roll tightly into a chimichanga.
Lightly spray or brush each chimichanga with olive oil or melted butter.
Preheat the air fryer to 375°F.
Place chimichangas seam-side down in the air fryer basket, leaving space between them.
Air fry for 10–12 minutes, flipping halfway, until golden brown and crispy.
Remove carefully and let cool slightly before serving.