Preheat your air fryer to 400°F (200°C) for about 5 minutes. This ensures the medallions cook evenly and achieve a nice sear.
Slice the pork tenderloin into 1-inch thick medallions. Pat them dry with paper towels to remove excess moisture, which helps the seasoning adhere better and promotes a good sear.
In a small bowl, mix together the salt, black pepper, garlic powder, paprika, dried thyme, and onion powder.
Rub the medallions with olive oil to help the seasoning stick and prevent them from drying out.
Sprinkle the seasoning mixture evenly over the medallions, pressing it into the meat to ensure good coverage.
Place the seasoned medallions in a single layer in the air fryer basket. Make sure they are not touching or overlapping, as this allows hot air to circulate around each piece for even cooking.
Cook at 400°F (200°C) for 10-12 minutes, flipping halfway through the cooking time to ensure both sides are evenly cooked and browned.
Use a meat thermometer to check the internal temperature. The medallions are done when they reach an internal temperature of 145°F (63°C).
Remove the medallions from the air fryer and let them rest for 5 minutes before serving. This helps the juices redistribute throughout the meat, ensuring they remain tender and juicy.
Serve with your favorite sides, such as roasted vegetables, mashed potatoes, or a fresh salad.