In a mixing bowl, combine the breadcrumbs, grated Parmesan cheese, Italian seasoning, garlic powder, onion powder, paprika, salt, and pepper. Mix well to evenly distribute the ingredients.
Drizzle 2 tablespoons of olive oil (or melted butter) into the breadcrumb mixture and stir until the mixture is slightly dampened. This helps the coating crisp up during baking.
Coat your chicken, pork, or vegetables in olive oil or an egg wash. Then, dip and coat thoroughly with the breadcrumb mixture, pressing gently to ensure it sticks.
Preheat your oven to 400°F (200°C). Place the coated items on a baking sheet and bake for 25-30 minutes (depending on thickness), or until golden and crispy.
Serve immediately with your favorite sides and dipping sauces. Enjoy your crispy, homemade Italian shake and bake!