In a small saucepan over medium heat, combine the brown sugar, pineapple juice, water, teriyaki sauce, soy sauce, lemon juice, minced garlic, and cayenne. Stir until the brown sugar dissolves.
Add the whiskey and bring to a gentle simmer. Cook 20-30 minutes, stirring occasionally, until reduced by half and thickened. Remove from heat and let rest.
Pat the salmon dry, brush with olive oil, and season with salt, pepper, and garlic powder.
Preheat the air fryer to 400°F (200°C). Place salmon in a single layer in the basket and air fry for 8-10 minutes, until it flakes easily and reaches 145°F.
Brush the glaze over the salmon during the last 2 minutes of cooking, then again before serving. Garnish with sesame seeds and green onions if desired.