Pat the pickle slices dry with paper towels to remove excess moisture.
Arrange three shallow bowls—one with flour, one with beaten eggs, and one with breadcrumbs mixed with paprika, garlic powder, salt, and pepper.
Dip each pickle slice into the flour, then the egg, and finally the breadcrumb mixture, pressing gently to coat evenly.
Preheat your air fryer to 400°F (200°C) for about 3 minutes.
Lightly spray the air fryer basket with cooking spray and place the breaded pickle slices in a single layer, leaving space between them.
Spray the tops of the pickles lightly with cooking spray and air fry for 6–8 minutes, flipping halfway through, until golden and crispy.
Let the pickle nickels cool slightly before serving them with your favorite dipping sauce.