In a small mixing bowl, combine the ketchup, lemon juice, Worcestershire sauce, hot sauce, and garlic powder.
Stir the ingredients together until well combined.
Taste the sauce and adjust the seasoning with salt and pepper to your liking.
Transfer the cocktail sauce to a serving dish and refrigerate for at least 30 minutes to allow the flavors to meld together.
Once chilled, give the sauce a final stir and serve alongside your favorite seafood dishes, such as shrimp, crab, or oysters.
Enjoy dipping and savoring the delicious flavor of your homemade Cocktail Sauce Without Horseradish!